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Stomatal aperture and turnover of ABA receptors are regulated by Arabidopsis ALIX
Plant Cell. 2019 Jul 30. García-León M, Cuyas L, Abd El-Moneim D, Rodriguez L, Belda-Palazon B, Sánchez-Quant E, Fernández Y, Roux B, Zamarreño AM, Garcia-Mina JM, Nussaume L, Rodriguez PL, Paz-Ares J, Leonhardt N, Rubio V. Abstract The plant endosomal...
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Mechanisms and phenotypic consequences of acquisition of tigecycline resistance by Stenotrophomonas maltophilia
J Antimicrob Chemother. 2019 Aug 1. Blanco P, Corona F, Martinez JL. Abstract OBJECTIVES: To elucidate the potential mutation-driven mechanisms involved in the acquisition of tigecycline resistance by the opportunistic pathogen Stenotrophomonas...
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Flower-like Mn-Doped Magnetic Nanoparticles Functionalized with αvβ3-Integrin-Ligand to Efficiently Induce Intracellular Heat after Alternating Magnetic Field Exposition, Triggering Glioma Cell Death.
ACS Appl Mater Interfaces. 2019 Jul 22 Del Sol-Fernández S, Portilla-Tundidor Y, Gutiérrez L, Odio OF, Reguera E, Barber DF, Morales MP Abstract Despite the potential of magnetic nanoparticles (NPs) to mediate intracellular hyperthermia when exposed to...
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An Evolutionarily Ancient Immune System Governs the Interactions between Pseudomonas syringae and an Early-Diverging Land Plant Lineage
Curr Biol. 2019 Jul 22;29(14):2270-2281 Gimenez-Ibanez S, Zamarreño AM, García-Mina JM, Solano R. Abstract Evolutionary molecular plant-microbe interactions (EvoMPMI) is an emerging field bridging the gap between molecular phytopathology and...
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Bacillus subtilis RecA interacts with and loads RadA/Sms to unwind recombination intermediates during natural chromosomal transformation
Nucleic Acids Res. 2019 Jul 27 Torres R, Serrano E, Alonso JC During natural transformation Bacillus subtilis RecA, polymerized onto the incoming single-stranded (ss) DNA, catalyses DNA strand invasion resulting in a displacement loop (D-loop)...
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Sterol isomerase HYDRA1 interacts with RNA silencing suppressor P1b and restricts potyviral infection
Plant, Cell & Environment 08 July 2019 J Ochoa de Eribe, A Valli, M Martín‐Trillo, C Simón‐Mateo, JA García, B Rodamilans. Abstract Plants use RNA silencing as a strong defensive barrier against virus challenges, and viruses counteract this defence by...
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Intermittency of Deformation and the Elastic Limit of an Icosahedral Virus under Compression
ACS Nano. 2019 Jun 26. Hernando-Pérez M, Zeng C, Miguel MC, Dragnea B. Abstract Viruses undergo mesoscopic morphological changes as they interact with host interfaces and in response to chemical cues. The dynamics of these changes, over the entire...
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Structural and functional analysis of the role of the chaperonin CCT in mTOR complex assembly
Nature Communications 10 , Article number: 2865 ( 2019 ) Jorge Cuéllar, W. Grant Ludlam, Nicole C. Tensmeyer, Takuma Aoba, Madhura Dhavale, César Santiago, M. Teresa Bueno-Carrasco, Michael J. Mann, Rebecca L. Plimpton, Aman Makaju, Sarah Franklin,...
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Genetic Interactions and Molecular Evolution of the Duplicated Genes ICARUS2 and ICARUS1 Help Arabidopsis Plants Adapt to Different Ambient Temperatures
Plant Cell. 2019 Jun;31(6):1222-1237. Méndez-Vigo B, Ausín I, Zhu W2, Mollá-Morales A, Balasubramanian S, Alonso-Blanco C. Abstract Understanding how plants adapt to ambient temperatures has become a major challenge prompted by global climate change....
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PD-1 signaling affects cristae morphology and leads to mitochondrial dysfunction in human CD8+ T lymphocytes
J Immunother Cancer. 2019 Jun 13;7(1):151. Ogando J, Sáez ME, Santos J, Nuevo-Tapioles C, Gut M, Esteve-Codina A, Heath S, González-Pérez A, Cuezva JM, Lacalle RA, Mañes S Abstract BACKGROUND: Binding of the programmed death-1 (PD-1) receptor to its...
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Why Do Leaves Rise with the Temperature?
Plant Physiol. 2019 Jun;180(2):691-692 Hayes S. No abstract available
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Bacterial Feature Finder (BaFF)-a system for extracting features overrepresented in sets of prokaryotic organisms
BIOINFORMATICS 2019, 14 feb López-Ibáñez J, Martín LT, Chagoyen M, Pazos F. Abstract MOTIVATION: The results of some experimental and computational techniques are given in terms of large sets of organisms, especially prokaryotic. While their...
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Pseudomonas putida in the quest of programmable chemistry
Curr Opin Biotechnol. 2019 Apr 29;59:111-121 Martínez-García E, de Lorenzo V. Abstract Traditional microbial biotechnology is in the midst of a profound transformation brought about not only by many conceptual and technical breakthroughs (e.g. systems...
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Age-related oxidative stress confines damage-responsive Bmi1+ cells to perivascular regions in the murine adult heart
Redox Biol. 2019 Apr;22:101156. Herrero D, Cañón S, Albericio G, Carmona RM, Aguilar S, Mañes S, Bernad A. Abstract Adult progenitor cells reside in specialized microenvironments which maintain their undifferentiated cell state and trigger regenerative...
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Dido3-dependent SFPQ recruitment maintains efficiency in mammalian alternative splicing
Nucleic Acid Research 2019 Apr 12019 Apr 1 Mora Gallardo C, Sánchez de Diego A, Gutiérrez Hernández J, Talavera-Gutiérrez A, Fischer T, Martínez-A C, van Wely KHM. Abstract Alternative splicing is facilitated by accessory proteins that guide...
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When nitrate and phosphate sensors meet
Nat Plants. 2019 Mar 25 Poza-Carrión C, Paz-Ares J Abstract Optimal plant growth requires an appropriate balance of mineral nutrients. A novel mechanism involving the physical interaction between nitrate and phosphate sensors in rice provides a...
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ParB dynamics and the critical role of the CTD in DNA condensation unveiled by combined force-fluorescence measurements
eLife 2019;8:e43812 Madariaga-Marcos J , Pastrana CL , Fisher GLM , Dillingham MS , Moreno-Herrero F Abstract Bacillus subtilis ParB forms multimeric networks involving non-specific DNA binding leading to DNA condensation. Previously, we found that an...
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3DBIONOTES v3.0: Crossing molecular and structural biology data with genomic variations
Bioinformatics. 2019 Feb 15. pii: btz118. Segura J, Sanchez-Garcia R, Sorzano COS, Carazo JM. Abstract MOTIVATION: Many diseases are associated to single nucleotide polymorphisms that affect critical regions of proteins as binding sites or post...
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Functional annotation of orthologs in metagenomes: a case study of genes for the transformation of oceanic dimethylsulfoniopropionate.
ISME J. 2019 Jan 14. González JM, Hernández L, Manzano I, Pedrós-Alió C. Abstract Dimethylsulfoniopropionate (DMSP) is produced mainly by phytoplankton and bacteria. It is relatively abundant and ubiquitous in the marine environment, where...
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T cells loaded with magnetic nanoparticles are retained in peripheral lymph nodes by the application of a magnetic field
J Nanobiotechnology 2019;17(1):14. Sanz-Ortega L, Rojas JM, Marcos A, Portilla Y, Stein JV, Barber DF. Abstract BACKGROUND: T lymphocytes are highly dynamic elements of the immune system with a tightly regulated migration. T cell-based transfer...